Figure 4 | Scientific Reports

Figure 4

From: Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity

Figure 4

Dose–response curves of 20d and 19b in A-549 (a) and HCT-116 (b) after 72 h of treatment cells determined by the MTT assay. All data are presented as mean ± SEM of three independent experiments in triplicates. (c,d) The effect of the examined compound on the colony-forming ability of HCT-116 cells. (c) Representative images of colonies formed by HCT-116 cells after treatment with different concentrations of 20d and 19b. (d) Quantitative analysis of clonogenicity assays. Error bars represent the SEM of data obtained from three independent experiments. **p < 0.001, ***p < 0.0001, and ****p < 0.00001 vs. vehicle.

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