Table 1 Top 10 up- and downregulated genes in the luseogliflozin-treated group.

From: Luseogliflozin preserves the pancreatic beta-cell mass and function in db/db mice by improving mitochondrial function

Upregulated

Fold-change

P-value

Downregulated

Fold-change

P-value

Gene symbol

Gene symbol

Fam151a

5.20

0.02

Spink3

0.09

 < 0.01

Cox6a2

4.33

0.01

Tm4sf20

0.11

 < 0.01

Slc2a2

3.98

 < 0.01

Cck

0.13

0.02

Top2a

3.63

 < 0.01

Pla2g1b

0.16

 < 0.01

Casc5

3.43

 < 0.01

Prss1

0.20

 < 0.01

Angptl7

3.23

 < 0.01

Gp2

0.21

0.03

Mki67

3.23

0.03

Pnliprp2

0.22

 < 0.01

Pbk

3.08

0.04

Pdia2

0.22

0.01

Ccna2

2.88

0.03

Cuzd1

0.22

0.02

Maob

2.82

 < 0.01

Serpini2

0.23

0.02

  1. P values were determined using Student’s t test.