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Figure 1

From: Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition

Figure 1

(a) Effect of Chebulinic acid (CA) on Vero E6 cells and dengue virus (DENV). (a) Cytotoxic effect of CA at various concentrations on Vero E6 cells. (b, d) Direct virucidal effect of CA at various concentrations on dengue virus infection at MOI = 0.1 in Vero E6 cells. Virus titer was assessed at 120 h post infection and expressed in terms of (b) Log10 viral RNA copies/µL and (c) Log10 focus forming units/ml, ***P value < 0.0001, *P < 0.05. (d) Percentage inhibition of DENV focus forming units/mL by CA compared to virus control (VC). All the experiments were performed in triplicates, and the data values are expressed as mean ± SEM.

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