Figure 3 | Scientific Reports

Figure 3

From: Analysis of MRI and CT-based radiomics features for personalized treatment in locally advanced rectal cancer and external validation of published radiomics models

Figure 3

Representative images from MRI (a,b) and CT (c,d) with corresponding Laplacian of Gaussian (LoG) transformed images from two patients (P) in the two response groups, i.e. responder: P1 and non-responder: P2 on the training data. Red contours mark the gross tumour volume (GTV). P1 (responder: TRG = 4) showed an overall homogenous appearance on the baseline MRI. On the contrary, P2 (non-responder: TRG = 1) showed a more heterogeneous GTV with a low stat_min value on the LoG transformed MR image, which corresponds to some high pixel intensities on the baseline MRI. Similarly, a more homogenous GTV (excluding the air voxels) can be seen in P1 compared to P2 on the baseline and LoG transformed CT slices, possibly causing low gradients in the intensity histogram for the responder.

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