Figure 7 | Scientific Reports

Figure 7

From: Long-lasting reflexive and nonreflexive pain responses in two mouse models of fibromyalgia-like condition

Figure 7

Dose–response effect of pregabalin acute treatment on mice subjected to reserpine-induced myalgia and intramuscular acid saline solution injection. Hind paw withdrawal latency in response to a thermal stimulus pre- and after Pregabalin administration in the (A) RIM6 and (B) ASI models and (C,D) percentage of analgesia 30 min after administration at 28 (RIM6) or 10 (ASI) days postinduction. Data are expressed as the mean ± SEM (n = 5 per group). *p < 0.05 Pre versus Post; n.s. = no significant differences; a–e: Groups not sharing a letter showed significant differences, p < 0.05, by post hoc tests.

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