Table 3 Comparison of the intensities of Toll-like receptor2 (TLR2) and TLR7 expression according to disease manifestations in adult onset Still’s disease.

From: Elevated expression of TLR2 and its correlation with disease activity and clinical manifestations in adult-onset Still’s disease

Manifestations

TLR2

p-value

TLR7

p-value

Fever

(+), n = 10

1.31 ± 0.58

0.579

1.22 ± 0.23

0.353

(−), n = 10

1.23 ± 0.19

 

1.34 ± 0.35

 

Sore throat

(+), n = 4

1.58 ± 0.92

0.892

1.42 ± 0.24

0.148

(−), n = 16

1.19 ± 0.17

 

1.24 ± 0.30

 

Skin rash

(+), n = 12

1.29 ± 0.53

0.678

1.22 ± 0.22

0.305

(−), n = 8

1.24 ± 0.21

 

1.37 ± 0.38

 

Lymphadenopathy

(+), n = 3

1.68 ± 1.10

0.765

1.23 ± 0.34

0.689

(−), n = 17

1.20 ± 0.16

 

1.29 ± 0.30

 

Hepatosplenomegaly

(+), n = 2

2.10 ± 1.21

0.126

1.59 ± 0.04

0.042

(−), n = 18

1.18 ± 0.16

 

1.25 ± 0.29

 

Arthritis

(+), n = 6

1.34 ± 0.18

0.020

1.44 ± 0.41

0.239

(−), n = 12

1.24 ± 0.50

 

1.21 ± 0.21

 
  1. These data were assessed using a Mann–Whitney U test.