Table 5 Toll-like receptor (TLR) immunostaining results in lymph node (LN) biopsies from patients with adult-onset Still’ disease (AOSD) and other similar conditions.

From: Elevated expression of TLR2 and its correlation with disease activity and clinical manifestations in adult-onset Still’s disease

 

Staining cell percent AOSD (n = 9)

Staining cell percent Tb lymphadenitis (n = 5)

p-value (AOSD vs. Tb lymphadenitis)

Staining cell percent T cell lymphoma (n = 5)

p-value (AOSD vs. T cell lymphoma)

Staining cell percent HNL (n = 5)

p-value (AOSD vs. HNL)

Staining cell percent reactive LN (n = 5)

p-value (AOSD vs. reactive LN)

TLR1

34.4 ± 17.9

13.2 ± 13.2

0.029

9.2 ± 6.2

0.004

24.0 ± 2.9

0.240

7.6 ± 7.6

0.004

TLR2

17.3 ± 16.6

6.8 ± 5.7

0.190

20.0 ± 31.8

0.438

4.8 ± 3.0

0.042

8.6 ± 4.7

0.518

TLR4

31.1 ± 13.6

44.0 ± 26.0

0.364

4.4 ± 3.4

0.001

52.0 ± 17.5

0.060

12.2 ± 7.2

0.012

TLR7

27.2 ± 20.0

32.0 ± 4.5

0.190

8.2 ± 7.2

0.019

49.0 ± 12.5

0.060

8.0 ± 2.7

0.002

TLR9

18.3 ± 9.7

11.2 ± 11.2

0.147

3.6 ± 4.0

0.002

21.0 ± 19.2

0.898

2.6 ± 1.7

0.001

  1. p-values determined using a Mann–Whitney U-test. AOSD, adult-onset Still’s disease; Tb, tuberculosis; HNL, histiocytic necrotizing lymphadenitis; LN, lymph node.
Back to article page