Table 2 Results of the comparison between CT-targeted versus non-CT-targeted stimulation of the penile shaft, CT-targeted and non-CT-targeted penile shaft versus frenulum stimulation and CT-targeted versus non-CT-targeted forearm stimulation.

From: A psychophysical and neuroimaging analysis of genital hedonic sensation in men

Condition	Region	Cluster size	T-value	x	y	z	FWE-corrected p value at peak-level
Penile shaft CT-targeted > Penile shaft non-CT-targeted	R Central operculum (S2)	54	3.96	52	− 4	6	< 0.1 *
	R Middle temporal gyrus & angular gyrus	104	3.92	58	− 58	14	n.s
			3.42	42	− 54	8
			3.34	50	− 56	12
Penile shaft non-CT-targeted > Penile shaft CT-targeted	L Pre-Supplementary Motor Area	132	4.45	− 8	6	56	n.s
Penile frenulum > Penile shaft CT-targeted	No suprathreshold clusters
Penile shaft CT-targeted > Penile frenulum	R Lateral occipital cortex (inferior), extending to middle temporal gyrus (MTG)	4017	5.96	50	− 60	12	< 0.005
			5.87	46	− 68	10
			5.77	44	− 56	8
	R Temporal occipital fusiform cortex	387	5.15	38	− 46	− 18	< 0.05
			3.93	32	− 34	− 18
			3.71	26	− 42	− 16
	R Posterior insula	76	4.47	34	− 18	0	< 0.05 *
	R Precuneus	263	4.36	16	− 60	12	n.s
	R Precuneus	263	3.56	16	− 48	− 2	n.s
	L Lateral occipital cortex (inferior)	187	4.19	− 44	− 74	12	n.s
	R Central operculum (S2), extending to planum temporale (STG)	292	4.06	64	− 10	6	n.s
			3.9	54	− 4	6
			3.49	52	− 18	10
	L Planum temporale and Hesch's gyrus	75	4.04	− 48	− 26	4	n.s
	R Superior temporal gyrus (STG)	57	3.92	58	− 6	− 12	n.s
	R Superior temporal gyrus (STG)	57	3.42	46	− 10	− 14	n.s
	R Lingual gyrus	68	3.74	22	− 60	− 10	n.s
	R Superior parietal lobule (SPL)	115	3.7	28	− 40	52	n.s
			3.61	32	− 54	56
			3.28	38	− 42	62
	L Anterior insula	31	3.59	− 34	8	− 12	n.s
Penile frenulum > Penile shaft non-CT-targeted	No suprathreshold clusters
Penile shaft non-CT-targeted > Penile frenulum	No suprathreshold clusters
Forearm CT-targeted > Forearm non-CT-targeted	No suprathreshold clusters
Forearm non-CT-targeted > Forearm CT-targeted	L Caudate nucleus	4695	5.55	− 16	− 6	18	< 0.005
			5.23	− 28	4	− 12
			5.1	− 26	8	− 4
	R Cerebellum	3993	5.43	18	− 60	− 22	< 0.005
			5.19	− 24	− 62	− 24
			4.62	30	− 60	− 28
	L + R Pre-Supplementary Motor Area, extending to anterior cingulate cortex	1197	5.11	− 6	4	60	< 0.01
			4.84	− 2	− 8	70
			4.71	− 8	− 14	70
	R Frontal pole	1584	4.78	46	46	− 4	< 0.05
			4.63	44	26	− 8
			4.57	38	32	18
	L Supramarginal gyrus (posterior division)	510	4.68	− 52	− 46	20	< 0.05
	L Supramarginal gyrus (posterior division)	510	4.35	− 62	− 40	16	< 0.05
	L Precentral gyrus	145	4.47	− 44	− 10	56	< 0.1
			3.55	− 34	− 12	64
			3.48	− 50	− 6	48
	L Hippocampus	149	4.38	− 20	− 22	− 8	n.s
	R Supramarginal gyrus (posterior division)	529	4.36	52	− 42	48	n.s
			4.29	48	− 36	42
			3.51	56	− 44	38
	L + R Anterior cingulate cortex	44	3.81	0	− 6	32	< 0.05 *
	R Middle temporal gyrus (temporooccipital part)	28	3.47	60	− 54	2	n.s

Only activity with a peak-level uncorrected p value < 0.001 and minimal cluster size of (k = 20) is reported. Regions were defined with the Harvard–Oxford Cortical Atlas. * Indicates that the cluster was only significant at an FWE-corrected threshold after applying small-volume correction (SVC). The SVC was applied for a mask containing all regions-of-interest (ROI’s). See Methods-section for more detail on ROI definition. Abbreviations: n.s., non-significant; R, right hemisphere; L, left hemisphere.

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Table 2 Results of the comparison between CT-targeted versus non-CT-targeted stimulation of the penile shaft, CT-targeted and non-CT-targeted penile shaft versus frenulum stimulation and CT-targeted versus non-CT-targeted forearm stimulation.

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