Figure 5
From: Alterations in metal homeostasis occur prior to canonical markers in Huntington disease
Cerebrospinal fluid mutant Huntingtin (mHTT) and Neurofilament light (NfL) in HD participants. CSF mHTT significantly increase with HD stage (A) and positively correlates with CAP-score (B) and negatively correlates with the composite Unified Huntington Disease Rating Scale (cUHDRS) (C). CSF NfL significantly increases with HD stage (D), and positively correlates with CAP-score (E) and negatively correlates with cUHDRS (F). An asterisk (*) indicates a p < 0.05 for post-hoc comparisons. Data are shown as individual data points with the mean ± sem .
