Figure 3
From: A comparative analysis of extracellular vesicles (EVs) from human and feline plasma
Nanoparticle tracking analysis of fractions 7–10 showing the size range and concentration of all EVs isolated from human and feline plasma. (a) NTA of particles isolated from human plasma shows that the peak in EV concentration is below 200 nm for fraction 7 (−) (mode: 168.0 ± 23.5 nm), fraction 8 (−) (mode: 170.0 ± 19.5 nm), fraction 9 (−) (mode 143.0 ± 15.8 nm) and fraction 10 (−) (mode: 176.3 ± 6.4 nm). A population of vesicles greater than 200 nm are also present in fraction 7 (D90: 286.6 ± 23.9 nm), fraction 8 (−) (D90: 347.6 ± 15.1 nm), fraction 9 (−) (D90: 275.0 ± 14.9 nm), fraction 10 (−) (D90: 300.9 ± 24.8 nm). (b) NTA of particles isolated from feline plasma shows the EV concentration is below 200 nm for fraction 7 (−) (mode: 110.0 ± 28.3 nm), fraction 8 (−) (mode: 172.0 ± 11.5 nm), fraction 9 (−) (mode: 137.0 ± 11.5 nm) and fraction 10 (−) (mode: 137.0 ± 20.4). A population of vesicles greater than 200 nm are also present in fraction 7 (−) (D90: 250.6 ± 8.7 nm), fraction 8 (−) (279.0 ± 17.4 nm), fraction 9 (−) (D90: 298.8 ± 13.0 nm), fraction 10 (−) (D90: 246.1 ± 28.7 nm).
