Table 1 Effect of crocin ± acrolein on anthropometric parameters in different studied groups.

From: Comparative study of oral versus parenteral crocin in mitigating acrolein-induced lung injury in albino rats

 

Control group

Cr group

Ac group (n10)

Oral-Cr/Ac group (n10)

ip-Cr/Ac group (n10)

p value

Oral-saline (n5)

ip-saline (n5)

Oral-Cr (n5)

ip-Cr (n5)

Body weight (gm)

242.6 ± 21.8

232.6 ± 23.6

233.5 ± 14.7

229.2 ± 16.4

201.3 ± 11.3a

221.4 ± 24.5

232.5 ± 18.2c

0.0031

Wet lung weight (gm)

1.4 ± 0.2

1.5 ± 0.4

1.6 ± 0.4

1.4 ± 0.6

2.3 ± 0.7a

1.9 ± 0.6

1.8 ± 0.4

0.0183

Lung index*

6.4 ± 2.1

6.5 ± 1.3

7.2 ± 3.1

7.9 ± 3.5

10.2 ± 0.7a

8.1 ± 1.3c

6.9 ± 0.9c

0.0013

Dry lung weight (gm)

0.52 ± 0.14

0.49 ± 0.1

0.5 ± 0.04

0.53 ± 0.05

0.6 ± 0.2

0.56 ± 0.6

0.62 ± 0.7

0.9966

W/D %

3.3 ± 1.1

2.9 ± 1.5

3.2 ± 0.7

3 ± 0.4

6.4 ± 1.7b

4.7 ± 1.3c

3.9 ± 0.6d

 < 0.001

  1. One-way ANOVA, and Tukey HSD Post-hoc Test, p > 0.05: no significant differences, p < 0.05: significant differences.
  2. *Lung index = wet lung weight (gr)/body weight (gr) × 1000; wet/ dry lung weight%.
  3. ap < 0.05 versus oral-saline group.
  4. bp < 0.001 significant versus oral-saline group.
  5. cp < 0.05 versus Ac group.
  6. dp < 0.001 significant versus Ac group.
  7. ep < 0.05 versus oral-Cr/Ac group.
  8. fp < 0.001 significant versus oral-Cr/Ac group.
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