Table 3 Fracture risk subgroup analyses according to the degree of underweight.

From: Severity of underweight and risk of fracture: a Korean nationwide population-based cohort study

Category

Hazard ratio (95% confidence interval)

P for interaction

Severe underweight

Moderate underweight

Mild underweight

Normal weight

Age

≥ 65 years

1.41 (1.27–1.56)

1.08 (1.00–1.16)

1.06 (1.01–1.10)

1

< 0.0001

< 65 years

1.22 (1.12–1.33)

1.21 (1.13–1.29)

1.16 (1.11–1.22)

1

 

Sex

Male

1.64 (1.47–1.82)

1.31 (1.22–1.41)

1.24 (1.18–1.31)

1

< 0.0001

Female

1.11 (1.02–1.21)

1.03 (0.97–1.10)

1.01 (0.97–1.06)

1

 

Hypertension

No

1.27 (1.17–1.37)

1.11 (1.05–1.18)

1.06 (1.02–1.10)

1

< 0.0001

Yes

1.29 (1.15–1.45)

1.19 (1.09–1.31)

1.18 (1.12–1.26)

1

 

Diabetes

No

1.27 (1.18–1.36)

1.13 (1.07–1.19)

1.08 (1.04–1.11)

1

< 0.0001

Yes

1.39 (1.13–1.72)

1.22 (1.03–1.43)

1.28 (1.16–1.42)

1

 
  1. Adjusted for age, sex, smoking status, drinking status, low income, regular exercise, diabetes, hypertension, dyslipidemia, and chronic kidney disease. There were no significant differences in other subgroup analyses, which included associations of fracture risk with smoking, drinking, regular exercise, low income, dyslipidemia, and chronic kidney disease.
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