Figure 6
From: Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD 1067
Transdermal delivery of MTD 1067-conjugated peptide and recombinant proteins in artificial skin model. Comparison of skin penetration (left) and permeability analysis using fluorescence intensity on the confocal image (right) were made with (a) FITC-labeled GHRP-6 and MTD-GHRP-6, (b) FITC-labeled des(1-3)IGF-I and MTD-des(1-3)IGF-I, (c) Rhodamine-labeled PDGF-BB and MTD-PDGF-BB. Each of the fluorescence intensity values per equivalent area are expressed as mean ± S.E. based on analysis of at least three independent images. Asterisks indicate statistical significance compared with the cargo control, as determined by the student's t-test (*p < 0.05, **p < 0.01, ***p < 0.001).
