Figure. 7
From: Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD 1067
Cell viability analysis using MTT assay (left panels) and cytotoxicity analysis using LDH assay (right panels) in HDFa cell. (a) GHRP-6 and MTD-GHRP-6, (b) des(1-3)IGF-I and MTD-des(1-3)IGF-I, (c) PDGF-BB and MTD-PDGF-BB. The μM concentrations correspond to 0, 8.7, 43.7, 87.3, 436.5 and 873 μg/mL for GHRP-6 and 0, 19.0, 94.9, 189.8, 949 and 1898 μg/mL for MTD-GHRP-6, respectively. Data are expressed as mean ± S.E. based on triplicates of at least two independent experiments. The results were expressed as % compared to the cell culture without treatment of the purified peptide or proteins.
