Figure 4
From: 3pHLA-score improves structure-based peptide-HLA binding affinity prediction
Performance of different scoring functions in evaluating the binding affinity of structures from the independent Dataset 3. Pearson’s correlation coefficient is indicated next to the name of the scoring function. Peptides involved in the structures of Dataset 3 (see Table S4) are listed on the y-axis. The peptide names and corresponding box plots are colored and arranged along the y-axis according to their experimental binding affinity (ranging from dark green, strong binders, at the top, to dark orange, non-binders, at the bottom). Predicted scores scaled to the range 1-0 are plotted on the x-axis (1-highest predicted binder; 0-non-binder). The correlation is calculated for the predicted binding affinity of each of the 82 structures present in Dataset 3 with respect to their experimental binding affinities.
