Table 1 Results of scoring functions obtained using different training protocols on the test set averaged across all HLA alleles for all four evaluated metrics (Pearson’s correlation coefficient |r|, Spearman’s correlation coefficient \(|\rho |\), the Area Under the Receiver Operator Curve AUROC and the Area Under the Precision Recall Curve AUPRC) . The highest values and best performing values in each column are bolded.

From: 3pHLA-score improves structure-based peptide-HLA binding affinity prediction

 

|r|

\(|\rho |\)

AUROC

AUPRC

3pHLA-score

0.75

0.90

0.98

0.99

standard-pHLA-score

0.46

0.50

0.80

0.82

ref2015-score

0.09

0.07

0.44

0.56