Table 1 Results of scoring functions obtained using different training protocols on the test set averaged across all HLA alleles for all four evaluated metrics (Pearson’s correlation coefficient |r|, Spearman’s correlation coefficient \(|\rho |\), the Area Under the Receiver Operator Curve AUROC and the Area Under the Precision Recall Curve AUPRC) . The highest values and best performing values in each column are bolded.
From: 3pHLA-score improves structure-based peptide-HLA binding affinity prediction
|r| | \(|\rho |\) | AUROC | AUPRC | |
|---|---|---|---|---|
3pHLA-score | 0.75 | 0.90 | 0.98 | 0.99 |
standard-pHLA-score | 0.46 | 0.50 | 0.80 | 0.82 |
ref2015-score | 0.09 | 0.07 | 0.44 | 0.56 |