Table 4 The differences of parameters between HCBS negative patients with MSA-C and SCA with a disease duration within 1 year.

From: Radiological hints for differentiation of cerebellar multiple system atrophy from spinocerebellar ataxia

  

Total (N = 61)

SCA (N = 46)

MSA-C (N = 15)

P value

Disease duration

 

0.90 ± 0.30

0.89 ± 0.31

0.93 ± 0.26

0.638

Cerebellum

NAA/Cr

0.89 ± 0.16

0.94 ± 0.13

0.74 ± 0.13

0.000

Cho/Cr

0.72 ± 0.16

0.75 ± 0.16

0.64 ± 0.12

0.000

Vermis

NAA/Cr

0.84 ± 0.09

0.86 ± 0.08

0.77 ± 0.08

0.001

Cho/Cr

0.67 ± 0.09

0.69 ± 0.09

0.62 ± 0.06

0.003

  

Total (N = 51)

SCA (N = 39)

MSA-C (N = 12)

P value

SARA score

 

7.15 ± 4.49

6.40 ± 4.22

9.58 ± 4.64

0.039

  1. Mann–Whitney test.
  2. Numeric data are presented as mean ± standard deviation.
  3. HCBS hot cross bun sign; MSA-C multiple system atrophy, cerebellar type; SCA spinocerebellar ataxia; SARA Scale for the Assessment and Rating of Ataxia; NAA N-acetyl aspartate; Cr creatinine; Cho Choline.
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