Table 4 Diagnostic results and post-neuroimaging findings.

(A)

At interim analysis

MRI findings

Periventricular Fazekas score ^a, No

0

3

3

1

0

0

0

0

1

1

10

2

2

9

1

3

2

1

7

4

4

15

0

4

3

0

1

1

0

5

4

3

Median

0

1

2

2

2

3

2

Subcortical Fazekas score, No

0

0

0

1

0

0

0

0

1

4

9

1

2

13

0

3

2

1

7

4

1

6

1

1

3

0

5

2

3

10

4

6

Median

1

2

2

2.5

2

3

3

Scheltens Scale ^b, No

0/1

4

3

0

2

0

0

2

2

1

6

2

2

4

1

0

3

0

9

5

1

13

1

4

4

0

3

1

1

12

3

4

Median

1

3

3

2

3

4

3

MRA head, No

Normal (0)

5

13

3

2

9

2

4

Mild (1)

0

7

2

2

12

1

4

Mild to moderate (2)

0

1

2

1

6

2

2

Moderate (3)

0

0

0

0

2

0

0

Moderate to severe (4)

0

0

1

0

0

0

0

Severe (5)

0

0

0

1

0

0

0

Median

0

0

1

1

1

1

1

ASL pattern, No

Normal (0)

4

9

5

2

7

4

5

AD pattern (1)

0

8

1

2

2

0

1

Non-AD pattern (2)

0

1

0

0

11

0

2

Non-specific pattern (3)

1

3

2

2

9

1

2

(B)

At final analysis

18F-Flutemetamol PET findings

Positivity of amyloid scanning ^c, No

1

11

2

0

26

2

0