Table 5 The integrated multi-omics data analysis revealed genes, proteins and metabolites that potentially correlate with bull fertility.
Pathway ID | KEGG pathway | Gene/translated protein | Significant function | Interacting metabolites |
|---|---|---|---|---|
bta00650 | Butanoate metabolism | ACADS, BDH1 | Sperm metabolism | Acetyl Co-A |
bta00010 | Glycolysis and Gluconeogenesis | SLC25A4, PFKL, PGM1 | Negative regulation of Apoptosis in sperm | S-maleate, l-Maleic acid |
bta00270 | Methionine and Cysteine Metabolism | AHCY, SMCP | Sperm motility, Oxidative phosphorylation | Taurine and hypotaurine |
bta04070 | Phosphatidyl inositol phosphate | PIP4K2C | Sperm motility and Acrosome reaction | Inositol-3.4, phosphate phosphotidyl 1-d-myoinositol |
bta00240 | Pyrimidine metabolism | POLR3K | Not identified | Carbamyol phosphate, dCTP, dUDP |
bta01212 | Saturated fatty acid beta oxidation | ACADS, GCDH | Sperm motility | Acetoacyl Co-A, acetyl Co-A |
bta00750 | Vit B metabolism | PNPO | Not identified | Pyridoxine phosphate |
