Figure 6

Exploitation of gene connectivity for LT PDAC survivor gene prioritization: (A) DADA-oriented multi-step disease module identification: PDAC seed gene selection (I), restriction to top 1% of ranked genes (II–III) and intersection of retained gene list with individual perturbation gene expression profiles for LT survivors (IV); (B) DADA-derived top-ranked genes found in at least one, two, or three LT survivors, indicated in green, orange and pink, respectively; (C) Common genes to DADA and other gene prioritization approaches: DEGs, clinically relevant WGCNA gene modules, and PEEPs;