Table 1 Classification of samples according to its multilocus sequencing type (MLST), core genome MLST (Complex type) and Staphylococcus aureus protein A (spa) per patient and year performed with SeqSphere+.

From: Evaluation of within-host evolution of methicillin-resistant Staphylococcus aureus (MRSA) by comparing cgMLST and SNP analysis approaches

  1. The change of MRSA strain appears clearly (orange) for patients 5, 9 and 12 therefore the samples (n = 4) were excluded from the calculations. Patient 10 has two of five samples with a different CT- and spa-type consequently, patient 10 was divided in two groups, patient 10.1 (dark colour) and patient 10.2 (light colour). Three samples (light yellow) were re-analyse for spa with Sanger sequencing due to failure with WGS to define spa. In addition, five more samples; two samples from patient 2, two samples from patient 6 and one sample from patient 16 were also sequenced with Sanger to verify the results obtained with WGS due to change of spa type within the patient during the follow up.
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