Table 2 Factor analysis of editing outcomes.

From: The cell cycle stage of bovine zygotes electroporated with CRISPR/Cas9-RNP affects frequency of Loss-of-heterozygosity editing events

 

Homozygous KO

Heterozygous KO

All non-mosaic KO

Mosaic KO

All KO

All mosaic

HPI

0.027*

0.046

0.002**

0.829

0.024*

0.152

PL

0.141

0.002**

 < 0.001***

0.005**

 < 0.001***

0.016*

HPIxPL

0.458

0.094

0.079

0.342

0.67

0.004**

  1. Analysis of effect of experimental factors on knockout type: GLMM of HPI, pulse length and their interaction on rate of homozygous, heterozygous and mosaic knockouts. Values are p values of each factor for each variable.
  2. *, ** and *** denote p values < 0.05, < 0.01 and < 0.001, respectively.
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