Figure 6

Transmission Electron Microscopy (TEM) results show the group as designed above. Images were taken at either 8000× or 20,000×. The 20,000× image was the enlarged image of 8000× in the black frame. In the 20,000×, the black arrow indicate characteristic autophagosome in A549 cells after treated with IL-7 (autophagosome decrease); cells treated with pifithrin‐α (autophagosome notably increase); cells treated with pifithrin‐α + IL-7 (autophagosome increase); cells treated with Compound C (autophagosome decrease); cells incubated with Compound C + IL-7 (autophagosome decrease); cells treated with A-IL-7R antibody + IL-7 (effect of IL-7-induced autophagosome depression was blunt); cells incubated with Rapamycin (autophagosome increase) and cells treated with IL-7 + Rapamycin (autophagyosome slightly increase).