Table 2 Relationship between P53 expression in NSCLC and clinical pathological factors (Chi-square test).

From: Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer

 

Patients

P53 high expression (%)

P value

χ2 value

Gender

Male

89

47 (52.81%)

  

Female

34

24 (70.59%)

0.102

3.187

Age

≤ 60

71

41 (57.75%)

  

> 60

52

30 (57.69%)

1.000

0.000

Histology

Squamous cancer

72

41 (56.94%)

  

Adenocarcinoma

51

30 (58.82%)

0.855

0.043

Differentiation

Well

16

9 (56.25%)

  

Moderate

55

33 (60%)

  

Poor

52

29 (55.77%)

0.899

0.212

Stage

I–II

56

25 (44.64%)

  

III

67

46 (68.66%)

0.01

7.208

mTOR expression

High

72

51 (70.83%)

  

Low

51

20 (39.22%)

0.001

12.229

AMPK expression

High

49

19 (38.78%)

  

Low

74

52 (70.27%)

0.001

11.983

IL-7 expression

High

89

62 (69.66%)

  

Low

34

9 (26.47%)

0.000

18.807

IL-7R expression

High

81

58 (71.6%)

  

Low

42

13 (30.95%)

0.000

18.731