Figure 5
From: Sp1 induced gene TIMP1 is related to immune cell infiltration in glioblastoma
Up-regulated TIMP1 expression is associated with poor outcomes of GBM. (A) Representative IHC images of TIMP1 staining in GBM tumors (magnification, ×3 and ×20 ). Blue color indicates staining for nuclei and brown color indicates staining for TIMP1 protein. (B) Kaplan–Meier analysis of overall survival and diseasE−free survival of 180 glioma patients. The low expression and high expression of TIMP1 were grouped by the IHC total score. Data were analyzed by log-rank test. (C) Univariate and multivariate regression analyses of TIMP1 for overall survival in glioma patients. Ki67 antigen identified by monoclonal antibody Ki-67, EGFR epidermal growth factor receptor, PDL1 programmed cell death protein−1.
