Table 3 Alteration of vision, macular fluid status, choroidal parameters, and PED area after different treatment modalities in eyes with vFIPED.
From: Flat irregular pigment epithelial detachment over time and outcome of different treatment regimens
PDT (n = 9) | IVB (N = 5) | Combination (N = 4) | Intergroup analysis P value | |
|---|---|---|---|---|
Overall | ||||
BCVA (logMAR) | ||||
Baseline | 0.60 ± 0.32 | 0.45 ± 0.24 | 0.38 ± 0.10 | 0.347 |
Treated | 0.56 ± 0.32 | 0.54 ± 0.21 | 0.23 ± 0.17 | 0.006 |
Within group P value | 0.118 | 0.075 | 0.006 | |
Intraretinal fluid | ||||
Baseline | 1 of 9 (11.1%) | 0 of 5 (0%) | 2 of 4 (50%) | 0.111 |
Treated | 1 of 9 (11.1%) | 1 of 5 (20%) | 0 of 4 (0%) | 0.638 |
Within group P value | 0.999 | 0.292 | 0.102 | |
Subretinal fluid | ||||
Baseline | 9 of 9 (100%) | 5 of 5 (100%) | 4 of 4 (100%) | – |
Treated | 5 of 9 (55.5%) | 5 of 5 (100%) | 2 of 4 (50%) | 0.174 |
Within group P value | 0.023 | – | 0.102 | |
TCA (mm2) | ||||
Baseline | 1.34 ± 0.40 | 1.44 ± 0.30 | 1.01 ± 0.14 | 0.260 |
Treated | 1.16 ± 0.25 | 1.46 ± 0.13 | 0.86 ± 0.19 | 0.029 |
Within group P value | 0.010 | 0.865 | < 0.001 | |
SCT (µm) | ||||
Baseline | 434 ± 121 | 379 ± 54 | 353 ± 56 | 0.396 |
Treated | 398 ± 87 | 352 ± 85 | 306 ± 68 | 0468 |
Within group P value | 0.036 | 0.087 | 0.003 | |
CVI | ||||
Baseline | 69.8 ± 2.97 | 69.8 ± 4.91 | 70.5 ± 3.91 | 0.944 |
Treated | 72.2 ± 2.52 | 69.1 ± 4.60 | 73.5 ± 3.37 | 0.086 |
Within group P value | 0.002 | 0.901 | < 0.001 | |
PED area (mm2) | ||||
Baseline | 0.760 ± 0.776 | NA | 1.162 ± 0.796 | 0.322 |
Treated | 0.411 ± 0.477 | NA | 1.153 ± 0.912 | 0.129 |
Within group P value | 0.235 | – | 0.967 | |
