Table 2 Comparison of clinical and genetic characteristics between sexes.
From: Distinct characteristics of central serous chorioretinopathy according to gender
Male (n = 249) | Female (n = 53) | Univariate p-value | |
|---|---|---|---|
Age | 55.1 ± 11.3 | 61.6 ± 12.4 | 2.1 × 10–4 |
Bilateral involvement | 72 (28.9%) | 11 (20.8%) | 0.23 |
Central retinal thickness (µm) | 314 ± 130 | 384 ± 170 | 0.003 |
Subfoveal choroidal thickness (μm) | 402 ± 115 | 331 ± 92 | 3.8 × 10–5 |
Baseline BCVA (log MAR) | 0.21 ± 0.37 | 0.23 ± 0.35 | 0.62 |
Descending tract | 45 (18.1%) | 0 (0%) | 8.0 × 10–4 |
Pachydrusen | 65 (26.1%) | 17 (32.1%) | 0.37 |
Fibrin | 16 (6.4%) | 3 (5.7%) | 0.83 |
Pigment epithelial detachment | 33 (13.3%) | 8 (15.1%) | 0.72 |
CFH I62V (rs800292) | |||
GG | 57 (22.9%) | 17 (32.1%) | |
GA | 129 (51.8%) | 22 (41.5%) | |
AA | 63 (25.3%) | 14 (26.4%) | |
A allele frequency | 51.2% | 47.2% | 0.45 |
CFH rs1329428 | |||
CC | 40 (16.1%) | 13 (24.5%) | |
CT | 138 (55.4%) | 24 (45.3%) | |
TT | 71 (28.5%) | 16 (30.2%) | |
T allele frequency | 56.2% | 52.8% | 0.52 |
