Figure 4 | Scientific Reports

Figure 4

From: Utilizing novel TBI-on-a-chip device to link physical impacts to neurodegeneration and decipher primary and secondary injury mechanisms

Figure 4

Elevation of acrolein-Lys adducts as a function of repeated impacts. Average intensity measurements for multiple impacts of 30 (A) and 200 g (B) rapidly (4–6 s) administered five and ten times. A single impact at both g forces levels is included for comparison. The increasing values displayed for both 30 and 200 g represent a cumulative effect of rapid, multiple impacts (note the difference in y-scale). Staining intensity is shown as percent control values ± SD (n = 18). One-way ANOVA and subsequent Scheffe post hoc analysis were used to determine significance: *p < 0.01.

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