Table 1 Characteristics of participants with and without T2DM.

From: Multi-block data integration analysis for identifying and validating targeted N-glycans as biomarkers for type II diabetes mellitus

Variable

Control

Case

Statistic

p

q

Age (mean ± SD)

55.10 ± 9.27

56.54 ± 9.89

 − 1.466t

0.0648

0.1102

Age (years)

31–40 years

8 (3.7)

14(6.0)

8.57^

0.073

0.1128

41–50 years

70(32.0)

50(21.6

   

51–60 years

83(37.9)

87(37.5)

   

61–70 years

44(20.1)

63(27.2)

   

71–80 years

14(6.4)

18(7.8)

   

Gender

Female

135 (61.4)

133 (57.30)

   

BMI (kg/m2)

  

1.302^

0.729

0.8262

Underweight

11(5.0)

7(3)

   

Normal

91(41.6)

102(44.2)

   

Overweight

74(33.8)

77(33.0)

   

Obese

43(19.6)

45(19.5)

   

Education

  

9.838^

0.043

0.0812

Tertiary

29(13.3)

40(17.2)

   

Senior high

72(33.0)

53(22.8)

   

Junior high

71(32.6)

76(32.8)

   

Lower primary

28(12.8)

28(12.1)

   

No formal education

18(8.3)

35(15.1)

   

Occupation

  

26.743^

0.0001*

0.0003**

Employed

147(67.4)

152(65.8)

   

Retired

21(9.6)

27(11.7)

   

Keeping house

14(6.4)

23(10.0)

   

Unemployed

26(16.6)

29(12.5)

   

Physical activity

Sedentary

30(13.8)

53(22.9)

9.772^

0.021

0.0446**

Moderate activity

114(52.3)

94(40.7)

   

Active

74(34.0)

84(36.3)

   

Clinical/biochemical data

WHtR

0.56 ± 0.08

0.56 ± 0.08

24057u

0.4933

0.599

SBP (mmHg)

145.96 ± 24.3

139.78 ± 24.91

20,863.5u

0.0035*

0.0084**

DBP (mmHg)

84.70 ± 14.42

82.52 ± 13.10

22652u

0.0925

0.131

FPG (mmol/l)

5.86 ± 0.95

9.24 ± 4.26

9871.5u

0.0000*

0.0001**

HbA1c (mmol)

5.45 ± 1.00

8.23 ± 2.09

9768.3u

0.0000*

0.0001**

TC (mmol/l)

4.69 ± 1.26

4.66 ± 1.26

21,918.5u

0.9604

0.9604

TG (mmol/l)

1.35 ± 0.97

1.24 ± 0.54

22,012.5u

0.8518

0.905

HDL-c (mmol/l)

1.24 ± 0.33

1.35 ± 0.33

17868u

0.0003*

0.0010**

LDL-c (mmol/l)

2.88 ± 1.05

2.74 ± 1.16

20,545.5u

0.254

0.3322

  1. Data presented as Mean ± SD and n (%). ^χ2 test of independence, tStudent’s t-test, uMann Whitney U tests. Tests of significance were two tailed (*p < 0.05); **q < 0.05F significant after correction for FDR and are bold.