Figure 4
From: The close interaction between hypoxia-related proteins and metastasis in pancarcinomas
Hypoxia score. (A) Hypoxia score mean across 13 PCA-TCGA types, and its validation with a pairwise map of significant Bonferroni correction (P < 0.001) across. (B) Mean frequency of hypoxia score per tumor stage, and its validation with the Bonferroni correction test. (C) Mean frequency of hypoxia score per metastatic status, and its validation with the Mann–Whitney U test (P < 0.001). TCGA: The Cancer Genome Atlas; BLCA: bladder urothelial carcinoma; BRCA: breast invasive carcinoma; CESC: cervical squamous cell carcinoma and endocervical carcinoma; CRC: colorectal adenocarcinoma; HNSC: head and neck squamous cell carcinoma; KIRC: kidney renal clear cell carcinoma; LIHC: liver hepatocellular carcinoma; LUAD: lung adenocarcinoma; LUSC: lung squamous cell carcinoma; PAAD: pancreatic adenocarcinoma; PRAD: prostate adenocarcinoma; SKCM: skin cutaneous melanoma; THCA: thyroid carcinoma; HS: hypoxia score.
