Table 4 Discriminating ability of the regular normative database on macular ganglion cell complex thickness for glaucoma detection.

From: Glaucoma diagnostic performance of macular ganglion cell complex thickness using regular and long axial length normative databases

 

Glaucoma (n = 185)

Normal (n = 102)

Regular normative database

Superior/inferior

 Abnormal thinning

159

27

 Within normal range

26

75

Sensitivity (95% CI)

0.859 (0.801–0.906)

 

Specificity (95% CI)

0.735 (0.639–0.818)

 

Positive likelihood ratio

3.25 (2.34–4.51)

 

Negative likelihood ratio

0.19 (0.13–0.28)

 

Positive predictive value

0.855 (0.809–0.891)

 

Negative predictive value

0.743 (0.665–0.808)

 

Accuracy

0.815 (0.766–0.859)

 

Regular normative database

GChart

 Abnormal thinning

169

26

 Within normal range

16

76

Sensitivity (95% CI)

0.914 (0.863–0.950)

 

Specificity (95% CI)

0.745 (0.649–0.826)

 

Positive likelihood ratio

3.58 (2.56–5.01)

 

Negative likelihood ratio

0.12 (0.07–0.19)

 

Positive predictive value

0.867 (0.823–0.901)

 

Negative predictive value

0.826 (0.746–0.885)

 

Accuracy

0.854 (0.807–0.893)

 
  1. CI Confidence Interval.
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