Table 5 Discriminating ability of the long axial database on macular ganglion cell complex thickness for glaucoma detection.

From: Glaucoma diagnostic performance of macular ganglion cell complex thickness using regular and long axial length normative databases

 

Glaucoma (n = 185)

Normal (n = 102)

p values (comparison between long axial and normal database)

Long database

Superior/inferior

 Abnormal thinning

159

12

 

 Within normal range

26

90

 

Sensitivity (95% CI)

0.860 (0.801–0.906)

 

p = 0.88

Specificity (95% CI)

0.882 (0.804–0.938)

 

p = 0.02**

Positive likelihood ratio

7.31 (4.28–12.47)

  

Negative likelihood ratio

0.16 (0.11–0.23)

  

Positive predictive value

0.930 (0.886–0.958)

  

Negative predictive value

0.776 (0.707–0.833)

  

Accuracy

0.868 (0.823–0.905)

  

Long normative database

GChart

   

 Abnormal thinning

165

15

 

 Within normal range

20

87

 

Sensitivity (95% CI)

0.892 (0.838–0.933)

 

p = 0.61

Specificity (95% CI)

0.853 (0.769–0.915)

 

p = 0.046**

Positive likelihood ratio

6.06 (3.79–9.70)

  

Negative likelihood ratio

0.13 (0.08–0.19)

  

Positive predictive value

0.917 (0.873–0.946)

  

Negative predictive value

0.813 (0.741–0.869)

  

Accuracy

0.878 (0.835–0.914)

  
  1. CI Confidence Interval.
  2. **Statistical significance shown at p < 0.05.