Table 5 Discriminating ability of the long axial database on macular ganglion cell complex thickness for glaucoma detection.
Glaucoma (n = 185) | Normal (n = 102) | p values (comparison between long axial and normal database) | |
|---|---|---|---|
Long database | |||
Superior/inferior | |||
Abnormal thinning | 159 | 12 | |
Within normal range | 26 | 90 | |
Sensitivity (95% CI) | 0.860 (0.801–0.906) | p = 0.88 | |
Specificity (95% CI) | 0.882 (0.804–0.938) | p = 0.02** | |
Positive likelihood ratio | 7.31 (4.28–12.47) | ||
Negative likelihood ratio | 0.16 (0.11–0.23) | ||
Positive predictive value | 0.930 (0.886–0.958) | ||
Negative predictive value | 0.776 (0.707–0.833) | ||
Accuracy | 0.868 (0.823–0.905) | ||
Long normative database | |||
GChart | |||
Abnormal thinning | 165 | 15 | |
Within normal range | 20 | 87 | |
Sensitivity (95% CI) | 0.892 (0.838–0.933) | p = 0.61 | |
Specificity (95% CI) | 0.853 (0.769–0.915) | p = 0.046** | |
Positive likelihood ratio | 6.06 (3.79–9.70) | ||
Negative likelihood ratio | 0.13 (0.08–0.19) | ||
Positive predictive value | 0.917 (0.873–0.946) | ||
Negative predictive value | 0.813 (0.741–0.869) | ||
Accuracy | 0.878 (0.835–0.914) | ||