Table 1 Baseline clinical features and pregnancy outcomes of the study population.
Characteristics | Pregnancy-associated HTN (−) (n = 1314) | Pregnancy-associated HTN ( +) (n = 33) | P-value |
|---|---|---|---|
Baseline characteristics | |||
Maternal age (years) | 32.3 ± 4.0 | 33.0 ± 4.7 | 0.518 |
Nulliparity | 671 (51.1%) | 21 (63.6%) | 0.211 |
Risk factors in clinical guidelines | |||
(1) High risk by the presence of either high- or moderate-risk factors | 188 (14.3%) | 14 (42.4%) | < 0.001 |
(2) High risk by the presence of one or more high-risk factors | 27 (2.1%) | 9 (27.3%) | < 0.001 |
a. Previous history of preeclampsia | 8 (0.6%) | 4 (12.1%) | < 0.001 |
b. Chronic hypertension | 7 (0.5%) | 4 (12.1%) | < 0.001 |
c. Pregestational diabetes | 15 (1.1%) | 2 (6.1%) | 0.063 |
d. Renal disease | 2 (0.2%) | 0 (0.0%) | 1.000 |
e. Autoimmune disease | 1 (0.1%) | 0 (0.0%) | 1.000 |
(3) High risk by the presence of two or more moderate-risk factors | 166 (12.6%) | 9 (27.3%) | 0.030 |
a. First pregnancy | 671 (51.1%) | 21 (63.6%) | 0.211 |
b. Old age (≥ 35 year) | 385 (29.3%) | 12 (36.4%) | 0.493 |
c. Obesity (BMI > 30 kg/m2) | 70 (5.3%) | 6 (18.2%) | 0.003 |
d. African race | 0 (0%) | 0 (0%) | (−) |
Pregnancy outcome | |||
Gestational age at delivery (weeks) | 39.0 ± 1.3 | 36.3 ± 3.0 | < 0.001 |
Gestational diabetes | 72 (5.7%) | 6 (20.0%) | 0.007 |
Birthweight at delivery (kg) | 3.2 ± 0.4 | 2.6 ± 0.8 | < 0.001 |
Infant sex (male) | 675 (51.4%) | 17 (51.5%) | 1.000 |
Infant admission to NICU | 53 (4.0%) | 9 (27.3%) | < 0.001 |
