Table 2 Correlation of ET-1 level in plasma or AqH to OCT/OCT-A parameters in glaucoma.

From: Elevated endothelin-1 levels as risk factor for an impaired ocular blood flow measured by OCT-A in glaucoma

Parameter

ET1-Plasma [pg/ml]

ET1-AqH [pg/ml]

rho

(p)

rho

(p)

Age at surgery

0.256

(0.035)

− 0.178

(0.20)

Refractive error

0.264

(0.031)

− 0.088

(0.53)

Visual acuity (LogMAR)

0.131

(0.29)

− 0.060

(0.67)

IOP

− 0.263

(0.030)

− 0.020

(0.89)

Cup/disc ratio vertical

0.261

(0.044)

0.029

(0.85)

Disc area

0.370

(0.004)

0.024

(0.87)

ONH Whole

− 0.080

(0.52)

0.066

(0.64)

PeriONH TempInf

− 0.246

(0.05)

0.201

(0.17)

PeriONH TempSup

− 0.348

(0.007)

− 0.001

(1.00)

Fovea SVP

− 0.323

(0.007)

0.177

(0.20)

Fovea DVP

− 0.331

(0.006)

0.204

(0.14)

FAZ

0.256

(0.035)

− 0.110

(0.43)

Topical antiglaucoma medications

− 0.126

(0.31)

0.374

(0.006)

RNFL Thickness Sup

− 0.242

(0.050)*

0.101

(0.48)

RNFL Thickness Inf

− 0.089

(0.48)

0.086

(0.55)

OCT GSS score

0.112

(0.38)

− 0.042

(0.78)

  1. The p-value p = 0.050* in the table indicates the significance of the corresponding test, that means p < 0.05.
  2. aCorrelation coefficient: Pearson’s rho for bivariate gaussian distributions, otherwise Spearman’s rho.
  3. bCorrelation test: Pearson’s method for bivariate gaussian distributions, otherwise Spearman’s method.
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