Figure 5


The nucleus accumbens showed a distinct pattern of the correlations between lipid metabolites. Color-coded correlation matrices of the amounts of lipid metabolites in the prefrontal cortex (a,b), the nucleus accumbens (c,d), the dorsal striatum (e,f), the amygdala (g,h), and the hippocampus (i,j) of stress-susceptible mice (a,c,e,g,i) and stress-resilient mice (b,d,f,h,j) are shown. Note that only the nucleus accumbens shows negative correlations in the pairs between a COX metabolite and a LOX metabolite in both stress-susceptible mice and stress-resilient mice. The same color coding is applied to all matrices. Color bars are shown in (a) and (g). *P < 0.05 for significant correlation by Pearson’s correlation test.