Figure 7 | Scientific Reports

Figure 7

From: Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice

Figure 7

Chronic social defeat stress increased the amount of the S isomer of 12-HETE in the nucleus accumbens. (a,b) Representative mass spectra of the R and S isomers of 12-HETE (a and b, respectively) in the nucleus accumbens of control and stress-resilient mice. The peaks of 12R-HETE and 12S-HETE are filled in blue. (c) The amounts of the R and S isomers of 12-HETE in the nucleus accumbens of control, stress-susceptible, and stress-resilient mice. The number of samples is shown below each bar. Values are expressed as means ± SEM. Tukey’s multiple comparisons test was used for statistical analyses. ****P < 0.0001 for the comparison between control and stress-resilient mice and †††P < 0.001 for the comparison between stress-susceptible and stress-resilient mice.

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