Figure 8 | Scientific Reports

Figure 8

From: Chronic social defeat stress increases the amounts of 12-lipoxygenase lipid metabolites in the nucleus accumbens of stress-resilient mice

Figure 8

Alox12 was expressed in blood vessel-like structures in the brain. (a) mRNA levels of Alox12 in the nucleus accumbens of control, stress-susceptible, stress-resilient mice. The values were determined by qRT-PCR and normalized by β-actin mRNA. The number of samples is shown below each bar. ns, not significant for Tukey’s multiple comparisons test. (b) Representative signals of in situ hybridization for Alox12 mRNA in the nucleus accumbens. Counterstaining was performed by Nissl staining. Brown dots represent signals. Signals on a blood vessel-like structure are indicated by red arrows. Scale bars: 200 μm and 50 μm for left and right images, respectively. (c) Alox12 mRNA expression in endothelial cells in the striatum. Publicly available data of single cell RNA-seq were analyzed with the interactive online software DropViz.

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