Figure 3 | Scientific Reports

Figure 3

From: Anxiety-like behavior and microglial activation in the amygdala after acute neuroinflammation induced by microbial neuraminidase

Figure 3

Parameters related to unsupported rearing, grooming, and freezing behaviors analyzed in the open field test. Rats were ICV-injected either with saline (Sal) or with neuraminidase (NA), and subjected to the open field test 2 weeks (2w) or 10 weeks (10w) after the ICV injection. Several parameters (total time, frequency, latency of the first episode, and the time/frequency ratio) related to the behaviors unsupported rearing (A–D), grooming (E–H) and freezing (I–L) were studied, and the mean values ± SEM (n = 11 for both NA and Sal) are represented in histograms. Student’s t-test were performed in order to check the influence of treatment (Sal versus NA) at both assessments. *p < 0.05.

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