Table 2 Clinical characteristics of Dataset 2.
Obese | Lean | p value | |
|---|---|---|---|
Men/Women | 7/18 | 9/15 | ns |
Age (years) | 47 ± 10 | 43 ± 9 | ns |
NGT/IFG&IGT/T2D | 10/9/6 | 23/1/0 | 0.007 |
BMI (kg/m2) | 40.7 ± 5.3 | 24.9 ± 3.2 | < 0.0001 |
Waist/Hip | 0.97 ± 0.12 | 0.87 ± 0.08 | 0.002 |
HbA1c (%) | 5.6 ± 0.5 | 5.2 ± 0.4 | 0.0006 |
MAP (mmHg) | 103 ± 11 | 90 ± 9 | 0.0005 |
Total cholesterol (mmol/L) | 4.3 ± 0.8 | 4.2 ± 0.7 | ns |
LDL cholesterol (mmol/L) | 2.6 ± 0.6 | 2.6 ± 0.9 | ns |
HDL cholesterol (mmol/L) | 1.2 ± 0.2 | 1.5 ± 0.4 | 0.01 |
Triglycerides (mmol/L) | 1.4 ± 0.5 | 1.0 ± 0.5 | 0.01 |
Fasting plasma glucose (mmol/L) | 5.7 ± 0.8 | 5.0 ± 0.4 | 0.003 |
Fasting plasma insulin (pmol/L) | 110 ± 72 | 45 ± 24 | < 0.0001 |
C-reactive protein (mg/dL) | 3.24 ± 2.12 | 0.67 ± 0.65 | < 0.0001 |
Circulating NAA (ng/mL) | 65.4 [11.6] | 62.8 [12.1] | ns |
Central NAA (mmol/L) | 9.1 [0.4] | 9.6 [0.7] | 0.001 |
Central TNAA (mmol/L) | 9.4 [0.7] | 10.0 [0.7] | 0.004 |
