Table 4 Results of the multivariate analysis (multivariate regression analysis).

From: Presence of periodontitis may synergistically contribute to cancer progression via Treg and IL-6

 

Estimate

95%CI

t-value

p value

VIF

A-IL6

Sex (female/male)

0.804

-5.574–7.182

0.250

0.801

1.489

Age

0.257

− 0.113–0.627

1.390

0.170

1.716

Brinkman index

− 0.002

− 0.019–0.016

− 0.200

0.840

1.993

Diabetes Mellitus (with/without)

2.077

− 8.874–13.028

0.380

0.705

1.248

Number of teeth

0.972

− 0.034–1.978

1.940

0.058

1.335

C − /C + 

− 7.534

− 14.739–0.328

− 2.100

0.041

2.101

C + P + /C + P −

14.903

5.057–24.749

3.040

0.004

1.517

B. Treg

Sex (female/male)

0.102

− 0.355–0.559

0.450

0.656

1.370

Age

-0.033

-0.060 –0.006

− 2.440

0.019

1.614

Brinkman index

0.000

− 0.001–0.001

0.160

0.871

1.655

Diabetes Mellitus (with/without)

0.097

− 0.756–0.950

0.230

0.820

1.074

Number of teeth

− 0.023

− 0.100–0.055

− 0.590

0.559

1.292

C − P − , C − P + , C + P − /C + P + 

− 0.774

− 1.235 to − 0.313

− 3.380

0.002

1.420

  1. C + : With cancer, C −: Without cancer.
  2. P + : With periodontitis, P −: Without periodontitis.
  3. CI: Confidential Interval, VIF: Variance Inflation Factor.