Figure 6 | Scientific Reports

Figure 6

From: Integrating a dynamic central metabolism model of cancer cells with a hybrid 3D multiscale model for vascular hepatocellular carcinoma growth

Figure 6

copyright 2010.

Spatial distribution of 6-phopshogluconate. The inhibition of glucose-6-phosphate dehydrogenase strongly influences cancer cell proliferation77,78,79 and may restore sensitivity of cancer cells to chemotherapy80. The figure shows schematically the structure of the spatial distribution of 6-phopshogluconate and the line points to its position in the metabolic network. Reprinted from53 under a CC BY license, with permission from BMC Systems Biology, original

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