Figure 6
Interaction, surface and thermodynamic properties of the K72A LTP1 variant. (a) Wt-LTP and K72A variant 3D structures and interaction network predicted using the DynaMut web tool. The surface topology (upper panel) and the different residues affected by mutation are indicated (lower panel). (b) 3D structure showing the vibrational entropy of the K72A variant. Red indicates an increase in entropy. The predicted values of enthalpy (ΔΔG) and vibrational entropy (ΔΔSvib) appear below the 3D model. (c) Volumetric properties of Wt-LTP and K72A variants determined by the VLDP web server. The values and differences in volume and surface area exposed to solvent between wild-type and K72A variants are indicated. (d) Electrostatic properties of Wt-LTP and K72A variants were generated using PyMol. Red: negative charge; blue: positive charge. Boxes highlight the zone of major differences.
