Table 1 Top 20 enriched pathway terms of DEGs in SARS-CoV-2 patients with lowest FDR values.
Pathway name | Entities P value | Entities FDR |
|---|---|---|
G1/S transition | 1.11E−16 | 1.75E−14 |
G1/S-specific transcription | 1.11E−16 | 1.75E−14 |
Cell cycle, mitotic | 1.11E−16 | 1.75E−14 |
Cell cycle | 1.11E−16 | 1.75E−14 |
Mitotic G1 phase and G1/S transition | 1.11E−16 | 1.75E−14 |
Cell cycle checkpoints | 1.11E−16 | 1.75E−14 |
Polo-like kinase mediated events | 4.04E−14 | 5.46E−12 |
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | 1.03E−13 | 1.08E−11 |
Amplification of signal from the kinetochores | 1.03E−13 | 1.08E−11 |
Resolution of sister chromatid cohesion | 1.77E−13 | 1.69E−11 |
Mitotic spindle checkpoint | 5.63E−13 | 4.84E−11 |
Mitotic prometaphase | 4.85E−12 | 3.63E−10 |
G2/M checkpoints | 4.97E−12 | 3.63E−10 |
EML4 and NUDC in mitotic spindle formation | 2.20E−11 | 1.47E−09 |
G0 and Early G1 | 4.48E−11 | 2.82E−09 |
M phase | 8.15E−11 | 4.81E−09 |
RHO GTPase effectors | 2.16E−10 | 1.19E−08 |
RHO GTPases activate formins | 3.14E−10 | 1.63E−08 |
DNA replication | 3.90E−10 | 1.95E−08 |
Activation of ATR in response to replication stress | 6.63E−10 | 3.12E−08 |