Table 1 Top 20 enriched pathway terms of DEGs in SARS-CoV-2 patients with lowest FDR values.

From: SARS-CoV-2 potential drugs, drug targets, and biomarkers: a viral-host interaction network-based analysis

Pathway name

Entities P value

Entities FDR

G1/S transition

1.11E−16

1.75E−14

G1/S-specific transcription

1.11E−16

1.75E−14

Cell cycle, mitotic

1.11E−16

1.75E−14

Cell cycle

1.11E−16

1.75E−14

Mitotic G1 phase and G1/S transition

1.11E−16

1.75E−14

Cell cycle checkpoints

1.11E−16

1.75E−14

Polo-like kinase mediated events

4.04E−14

5.46E−12

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

1.03E−13

1.08E−11

Amplification of signal from the kinetochores

1.03E−13

1.08E−11

Resolution of sister chromatid cohesion

1.77E−13

1.69E−11

Mitotic spindle checkpoint

5.63E−13

4.84E−11

Mitotic prometaphase

4.85E−12

3.63E−10

G2/M checkpoints

4.97E−12

3.63E−10

EML4 and NUDC in mitotic spindle formation

2.20E−11

1.47E−09

G0 and Early G1

4.48E−11

2.82E−09

M phase

8.15E−11

4.81E−09

RHO GTPase effectors

2.16E−10

1.19E−08

RHO GTPases activate formins

3.14E−10

1.63E−08

DNA replication

3.90E−10

1.95E−08

Activation of ATR in response to replication stress

6.63E−10

3.12E−08