Table 2 Clinical parameters during weaning from mechanical ventilation.

From: Nutritional support for successful weaning in patients undergoing prolonged mechanical ventilation

Group

Successful extubation

p-value

Failed weaning

p-value

Timeline

Initiation

Termination

Initiation

Termination

Weight (kg)

63.2 ± 14.7

59.9 ± 14.5

 < 0.001**

60.6 ± 12.2

60.2 ± 11.6

0.284

BMI (kg/m2)

23.9 ± 5.0

22.7 ± 4.8

 < 0.001**

23.2 ± 4.2

23.0 ± 3.8

0.281

APACHE II score

18.3 ± 3.6

10.1 ± 6.8

 < 0.001**

19.9 ± 4.6

20.6 ± 7.8

0.436

Caloric intake (kcal/kg/day)

23.8 ± 7.8

27.8 ± 9.1

 < 0.001**

24.5 ± 7.9

25.6 ± 7.5

0.051

Protein intake (g/kg/day)

0.97 ± 0.36

1.14 ± 0.42

 < 0.001**

1.01 ± 0.37

1.03 ± 0.36

0.348

Albumin (g/dl)

3.16 ± 0.6

3.29 ± 0.6

0.001**

3.04 ± 0.6

3.09 ± 0.6

0.236

Prealbumin (mg/dl)

19.7 ± 7.3

21.6 ± 6.9

0.025*

17.8 ± 7.9

22.0 ± 8.1

0.062

Hemoglobin (g/dl)

10.7 ± 2.3

11.0 ± 2.2

0.028*

9.83 ± 1.9

9.62 ± 2.0

0.159

BUN (mg/dl)

34.0 ± 27.9

35.9 ± 35.4

0.369

43.6 ± 36.0

42.8 ± 35.4

0.747

Creatinine (mg/dl)

1.72 ± 2.2

1.69 ± 2.4

0.707

1.80 ± 1.8

1.73 ± 1.6

0.369

Potassium (mmol/l)

4.10 ± 0.58

4.19 ± 0.67

0.107

4.12 ± 0.7

4.21 ± 0.8

0.188

Calcium (mg/dl)

8.25 ± 0.78

8.31 ± 1.08

0.697

8.54 ± 1.0

8.56 ± 0.9

0.817

Magnesium (mg/dl)

2.29 ± 0.46

2.30 ± 0.44

0.869

2.35 ± 0.4

2.29 ± 0.6

0.287

Phosphorus (mg/dl)

5.37 ± 2.1

4.74 ± 2.3

0.078

3.47 ± 1.9

4.18 ± 2.2

0.309

CRP (mg/dl)

4.85 ± 5.3

3.59 ± 5.1

0.006**

7.06 ± 6.8

6.68 ± 7.2

0.439

  1. Continuous data are expressed as mean ± SD. The p values are from paired t test for continuous variables for within-group comparisons. *The p value < 0.05 and **p value < 0.01 are considered statistically significant and extremely significant, respectively.
  2. BMI Body Mass Index, APACHE II score Acute physiology assessment and chronic health evaluation II score, BUN blood urea nitrogen, CRP high sensitivity C reactive protein.
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