Figure 4
From: Zoledronate combined metal-organic frameworks for bone-targeting and drugs deliveries
(A) TEM images of ZZF@PVP loaded with (a) DOX, (b) BSA, and (c) siRNA. Scale = 100 nm. (B) FTIR spectra of ZZF@PVP, free DOX, DOX@ZZF@PVP, free BSA, and BSA@ZZF@PVP. (C) UV–vis spectra of free siRNA, siRNA@ZZF@PVP, ZZF@PVP NPs, and the supernate of the as-synthesized siRNA@ZZF@PVP after centrifugation. (D,E) DOX and BSA release profiles for DOX and BSA loaded ZZF@PVP at pH 5.5 and 7.4.
