Figure 7 | Scientific Reports

Figure 7

From: Sulindac acetohydrazide derivative attenuates against cisplatin induced organ damage by modulation of antioxidant and inflammatory signaling pathways

Figure 7

Representative H & E images of rat liver and kidney from all treatment groups. (a) Liver tissue sections from saline and DMSO groups present a typical hepatic structure. CDPP-treated liver sections revealed higher cellular lacerations, structural derangements, and assembly of inflammatory cells. DMFM + CDDP treated liver sections showed near to normal morphology. DMFM treatment showed normal morphology as in control rats. (b) Kidney section from saline and DMSO groups showing normal kidney morphology. CDPP-treated rat kidney section showing enhanced cellular lesions, ballooning, and collection of inflammatory cells. DMFM + CDDP treated sections with minor tubular deteriorations. DMFM alone treatment showed normal morphology as in control rats. Treatment conditions are indicated at the lower left of each image.

Back to article page