Table 1 Clinical and laboratory characteristics of aPL- and AF-stroke patients.

From: Neuroimaging features of antiphospholipid antibody-related stroke compared with atrial fibrillation-related stroke

 

aPL-stroke (n = 56)

AF-stroke (n = 333)

p-value

Age, years

61 [48; 68]

76 [68; 81]

 < 0.001

Sex, male

27 (48.2)

189 (56.8)

0.30

Body mass index, kg/m2

23.7 ± 3.5

23.3 ± 3.4

0.52

Hypertension

39 (69.6)

239 (71.8)

0.87

Diabetes

12 (21.4)

111 (33.3)

0.11

Hyperlipidemia

25 (44.6)

131 (39.3)

0.55

Previous stroke

4 (7.1)

66 (19.8)

0.036

Ever smoker

25 (44.6)

93 (27.9)

0.018

Previous medication

Antiplatelet

11 (19.6)

132 (39.8)

0.006

Anticoagulant

3 (5.4)

65 (19.5)

0.017

Neurologic status

Initial NIHSS score

3 [1; 5.5]

5 [2; 14]

0.003

Discharge NIHSS score

1 [0; 4]

2 [1; 8]

0.015

Discharge mRS

1 [1; 2]

2 [1; 4]

0.003

Intravenous thrombolysis

3 (5.5)

52 (15.6)

0.067

Endovascular treatment

3 (5.5)

63 (18.9)

0.021

White blood cells, × 109/L

8.425 [6.040; 10.875]

7.480 [6.250; 9.410]

0.22

Hematocrit, %

40.6 [36.4; 45.0]

40.0 [35.9; 44.4]

0.50

Platelets, × 109/L

234 [195.5; 268.5]

201 [167; 233]

 < 0.001

Creatinine, mg/dL

0.86 [0.70; 0.99]

0.90 [0.74; 1.12]

0.061

Fasting glucose, mg/dL

97.5 [85; 106]

100 [87; 124]

0.034

LDL cholesterol, mg/dL

118 [87.5; 152]

96.5 [71; 125]

0.002

PT-INR

0.97 [0.94; 1.01]

1.03 [0.97; 1.11]

 < 0.001

Fibrinogen, mg/dL

334 [293; 384]

320 [280; 372]

0.20

hsCRP, mg/dL

0.15 [0.10; 0.56]

0.23 [0.08; 0.81]

0.38

LVIDd, cm

4.7 [4.5; 5.0]

4.7 [4.4; 5.0]

0.44

LVIDs, cm

2.9 [2.7; 3.1]

3.0 [2.7; 3.2]

0.72

IVSd, cm

0.9 [0.8; 1.0]

1.0 [0.9; 1.1]

0.040

LVPWd, cm

0.9 [0.9; 1.0]

1.0 [0.9; 1.0]

0.14

LV mass index, g/m2

89.0 [77.6; 106.2]

93.4 [78.6; 109.0]

0.35

LV ejection fraction, %

61 [57.5; 65]

60 [56; 64]

0.18

Left atrial size, mm

39 [35; 43]

49 [43; 53]

 < 0.001

Subclinical valve lesion

8 (14.3)

67 (20.1)

0.40

  1. The data were expressed as numbers (%), mean ± standard deviation, or median (interquartile range).
  2. AF-stroke atrial fibrillation-related stroke, aPL-stroke antiphospholipid antibody-related stroke, hsCRP high-sensitivity C-reactive protein, IVSd interventricular septal thickness at end-diastole, LDL low-density lipoprotein, LV left ventricular, LVIDd LV internal diameter at end-diastole, LVIDs LV internal diameter at end-systole, LVPWd LV posterior wall thickness at end-diastole, mRS modified Rankin Scale, NIHSS National Institutes of Health Stroke Scale, PT-INR prothrombin time-international normalized ratio.
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