Table 2 Area under the receiver operating characteristic for all Neurodevelopmental scores.

From: MRI based radiomics enhances prediction of neurodevelopmental outcome in very preterm neonates

Outcome (N = 19)

Gestational age only

Clinical variables

T1-Radiomics

T2-Radiomics

T1/2-Radiomics

Clinical + radiomics

Bayley-III Cognitive Composite Score 18 M

0.72 (0.631–0.816)

0.76 (0.66–0.854)

0.63 (0.519–0.74)

0.69 (0.578–0.796)

0.69 (0.59–0.799)

0.79 (0.708–0.874)

Bayley-III Language Composite Score 18 M

0.66 (0.570–0.755)

0.6 (0.5–0.694)

0.64 (0.555–0.735)

0.5 (0.399–0.603)

0.66 (0.574–0.752)

0.64 (0.55–0.733)

Bayley-III Motor Composite Score 18 M

0.70 (0.615–0.789)

0.64 (0.551–0.736)

0.59 (0.493–0.687)

0.6 (0.5–0.692)

0.6 (0.507–0.702)

0.61 (0.509–0.704)

PDMS-2 fine motor quotient 18 M

0.69 (0.514–0.859)

0.58 (0.35–0.817)

0.52 (0.33–0.716)

0.49 (0.312–0.663)

0.34 (0.168–0.515)

0.45 (0.287–0.614)

PDMS-2 gross motor quotient 18 M

0.75 (0.665–0.828)

0.71 (0.626–0.8)

0.64 (0.55–0.737)

0.7 (0.604–0.786)

0.71 (0.618–0.794)

0.73 (0.647–0.818)

PDMS-2 total motor quotient 18 M

0.74 (0.657–0.83)

0.72 (0.618–0.826)

0.81 (0.74–0.883)

0.66 (0.56–0.759)

0.81 (0.743–0.886)

0.83 (0.752–0.899)

PDMS-2 fine motor quotient 33 M

0.69 (0.56–0.812)

0.53 (0.343–0.723)

0.55 (0.41–0.69)

0.54 (0.384–0.697)

0.56 (0.411–0.7)

0.53 (0.38–0.671)

PDMS-2 gross motor quotient 33 M

0.65 (0.537–0.762)

0.57 (0.443–0.697)

0.77 (0.676–0.869)

0.7 (0.595–0.807)

0.75 (0.652–0.856)

0.75 (0.651–0.846)

PDMS-2 total motor quotient 33 M

0.72 (0.619–0.827)

0.68 (0.555–0.807)

0.64 (0.52–0.766)

0.69 (0.565–0.813)

0.61 (0.478–0.743)

0.6 (0.471–0.728)

Bayley-III cognitive composite score 33 M

0.51 (0.353–0.667)

0.42 (0.261–0.575)

0.66 (0.503–0.81)

0.53 (0.387–0.678)

0.61 (0.436–0.779)

0.59 (0.418–0.765)

WPPSI-IV Full IQ 4.5Y

0.53 (0.397–0672)

0.49 (0.339–0.649)

0.58 (0.437–0.724)

0.49 (0.325–0.647)

0.51 (0.359–0.654)

0.51 (0.36–0.654)

Bayley-III Motor Composite Score 33 M

0.69 (0.58–0.792)

0.68 (0.548–0.817)

0.72 (0.621–0.822)

0.64 (0.505–0.78)

0.68 (0.567–0.79)

0.6 (0.477–0.727)

WPPSI-IV Performance IQ 4.5Y

0.66 (0.447–0.876)

0.53 (0.27–0.798)

0.6 (0.482–0.726)

0.7 (0.52–0.881)

0.68 (0.535–0.818)

0.6 (0.449–0.752)

WPPSI-IV Verbal IQ 4.5Y

0.55 (0.365–0.735)

0.5 (0.291–0.716)

0.52 (0.322–0.726)

0.37 (0.17–0.563)

0.49 (0.277–0.697)

0.48 (0.285–0.679)

PDMS-2 fine motor quotient 4.5Y

0.63 (0.455–0.811)

0.56 (0.369–0.757)

0.56 (0.376–0.739)

0.48 (0.293–0.666)

0.59 (0.412–0.759)

0.57 (0.396–0.745)

Bayley-III Language Composite Score 33 M

0.73 (0.561–0.889)

0.71 (0.492–0.919)

0.65 (0.468–0.824)

0.68 (0.506–0.854)

0.62 (0.394–0.856)

0.66 (0.457–0.863)

WPPSI-IV processing speed IQ 4.5Y

0.72 (0.594–0.838)

0.72 (0.585–0.845)

0.7 (0.566–0.829)

0.74 (0.612–0.872)

0.71 (0.583–0.836)

0.69 (0.565–0.823)

PDMS-2 gross motor quotient 4.5Y

0.75 (0.579–0.912)

0.78 (0.629–0.927)

0.64 (0.453–0.818)

0.78 (0.635–0.934)

0.8 (0.659–0.932)

0.84 (0.729–0.956)

PDMS-2 total motor quotient 4.5Y

0.66 (0.472–0.856)

0.73 (0.545–0.913)

0.57 (0.366–0.765)

0.8 (0.654–0.945)

0.69 (0.53–0.856)

0.71 (0.545–0.877)

  1. Mean area under the receiver operating characteristic (AUROC) with 95% confidence interval (95% CI) are shown. AUROC ≥ 75% marked in bold. PDMS-2 Peabody Developmental Motor Scales, second edition, WPPSI-IV Wechsler Primary and Preschool Scale of Intelligence, fourth edition, IQ intelligence quotient, m months, y years.
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