Figure 2
Two representative cases (A, B) with primary open-angle glaucoma showing progressive reduction of circumpapillary vessel density (cpVD) and visual field (VF) progression. (A) Representative case of a 76-year-old man with a VF mean deviation of − 10.95 dB at baseline demonstrated VF progression preceded by cpVD reduction. Significant progressive VF progression (“likely progression”) was detected on September 14, 2018. Approximately four months later, two consecutive optical coherence tomography angiography (OCTA) tests (on September 14, 2018, and January 21, 2019) showed cpVD reduction \(\ge\) the tolerance limit (5.16 %) compared to baseline cpVD. B. Representative case of a 72-year-old female with VF MD, − 13.43 dB at baseline whose cpVD significantly decreased before VF progression was detected. Two consecutive OCTA tests on February 21, 2019, and November 4, 2020, showed cpVD reduction \(\ge\) the tolerance limit (5.16 %) compared to the baseline cpVD. VF progression was detected on April 2, 2021. cpVD circumpapillary vessel density, dB decibel, EMGT Early Manifest Glaucoma Trial, MD mean deviation, OCTA optical coherence tomography angiography, VF visual field.
