Figure 7
IL-12 overcomes reduced blinatumomab efficacy in the B-ALL secretome. (A) Representative flow cytometry plots of T-cell cytolytic activity showing leukemia cell death in different experimental conditions. (B) Leukemia cell death from T-cell cytolytic killing cultured in either control media (top panel) or Nalm6 supernatant (bottom panel) (n = 4 donors; *P < 0.05; **P < 0.01; ****P < 0.0001, ANOVA with Tukey multiple comparisons test).
